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TRIM72 Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 221511AP

Catalog No. 50-173-3746


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Description

Description

Muscle-specific protein that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Specifically binds phosphatidylserine. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. Required for transport of DYSF to sites of cell injury during repair patch formation. Regulates membrane budding and exocytosis. May be involved in the regulation of the mobility of KCNB1-containing endocytic vesicles.
Specifications

Specifications

TRIM72
0.77 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q1XH17, Q6ZMU5
hMG53, Mg53, Mitsugumin 53, TRIM72, tripartite motif containing 72
Rabbit
IgG
150 μL
-20°C
Primary
434246, 493829
Immunoprecipitation, Western Blot
Unconjugated
TRIM72
Liquid
Trim72
TRIM72 Fusion Protein Ag17756
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
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