Alfa Aesar™ (Trimethylsilyl)diazomethane, 2M in hexanes

Manufacturer: Alfa Aesar™ H26744AC

Quantity 25mL

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Catalog No. AAH26744AC

    N/A

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    Chemical Identifiers

    CAS 18107-18-1
    Molecular Formula C4H10N2Si
    Formula Weight 114.22g/mol
    MDL Number MFCD00053946
    UN Number UN3383
    Beilstein 1902903
    Synonym (Diazomethyl)trimethylsilane
    Chemical Name or Material (Trimethylsilyl)diazomethane

    Specifications

    Concentration 2M in hexanes
    Quantity 25mL
    Flash Point −23°C (−10°F)
    CAS 18107-18-1
    Molecular Formula C4H10N2Si
    Formula Weight 114.22g/mol
    MDL Number MFCD00053946
    UN Number UN3383
    Beilstein 1902903
    Synonym (Diazomethyl)trimethylsilane
    Health Hazard 1 Danger
    Health Hazard 2 GHS H Statement
    H225-H331-H350-H304-H361-H373-H315-H336
    Highly flammable liquid and vapor.
    Toxic if inhaled.
    May cause cancer.
    May be fatal if swallowed and enters airways.
    Suspected of damaging fertility or the unborn child.
    May cause damage to organs through prolonged or repeated exposure.
    Causes skin irritation.
    May cause drowsiness or dizziness.
    Health Hazard 3 GHS P Statement
    P210-P260-P301+P310-P303+P361+P353-P405-P501a
    Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
    Do not breathe dust/fume/gas/mist/vapors/spray.
    IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
    IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.
    DOT Information Transport Hazard Class: 6.1; Packing Group: I; Proper Shipping Name: TOXIC BY INHALATION LIQUID, FLAMMABLE, N.O.S.
    Chemical Name or Material (Trimethylsilyl)diazomethane

    Description

    Applications
    (Trimethylsilyl)diazomethane is used as a methylating agent in organic chemistry. It is utilized in Gas Chromatography- Mass-Spectrometry (GC-MS) for the analysis of various carboxylic compounds. It is involved as a reagent in the Doyle-Kirmse reaction with allyl sulfides and allyl amines. It is considered and used as a less-explosive replacement fordiazomethane. It is also used as a reactant for Unnatural alfa-amino acid derivatives containing gem-bisphosphonates through Michael addition reaction, imidazolo[2,1-b]benzothiazole derivatives and aigialomycin D analogues.

    Solubility
    Immiscible with water. Miscible with organic solvents.

    Notes
    (Trimethylsilyl)diazomethane (TMSD) in alcoholic solvents under acidic or basic conditions can lead to the formation of diazomethane. TMSD is under review by the National Toxicological Program for potential inhalation hazards.Incompatible with oxidizing agents, chlorine, fluorine and perchlorates.

    GHS H Statement
    H225-H331-H350-H304-H361-H373-H315-H336
    Highly flammable liquid and vapor.
    Toxic if inhaled.
    May cause cancer.
    May be fatal if swallowed and enters airways.
    Suspected of damaging fertility or the unborn child.
    May cause damage to organs through prolonged or repeated exposure.
    Causes skin irritation.
    May cause drowsiness or dizziness.

    GHS P Statement
    P210-P260-P301+P310-P303+P361+P353-P405-P501a
    Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
    Do not breathe dust/fume/gas/mist/vapors/spray.
    IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
    IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.

    Danger

    SDS & Safety Documents

  • Description & Specifications
  • Safety and Handling

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