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TRIP10 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA548688

Catalog No. PA548688

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Predicted to react with mouse and rat based on sequence homology.

Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling. Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N- WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.
Specifications

Specifications

TRIP10
Polyclonal
PBS with 0.09% sodium azide
Q15642
Cdc42-interacting protein 4, Protein Felic, Salt tolerant protein, hSTP, Thyroid receptor-interacting protein 10, TR-interacting protein 10, TRIP-10, TRIP10, CIP4, STOT, STP
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
9322
Western Blot
Unconjugated
TRIP10
Liquid
TRIP10
KLH conjugated synthetic peptide between 115-144 amino acids from the N-terminal region of human TRIP10.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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