TRIP13 Mouse anti-Human, Clone: OTI2F5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527201
DescriptionThyroid hormone receptors (TRs) are transcription factors that regulate the expression of specific genes in a hormone-dependent manner. TRIP13 (thyroid hormone receptor interactor 13), also called 16E1BP, is a transcription factor that interacts with the ligand binding domain of the thyroid receptor (TR) as well as a variety of target genes including human papilloma virus type 16 (HPV16) E1. Unlike most TRIP proteins which function only in the presence of hormones, TRIP13 does not require the presence of thyroid hormone to interact with TR. The association of TRIP13 with (HPV16) E1 suggests that TRIP13 may have tumor suppressor gene function. TRIP13 is a 432 amino acid protein with 2 different isoforms produced by alternative splicing.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|16E1BP, 16E1-BP, HPV16 E1 protein binding protein, HPV16 E1 protein-binding protein, TR-interacting protein 13, TRIP-13, human papillomavirus type 16 E1 protein-binding protein, pachytene checkpoint protein 2 homolog, thyroid receptor interacting protein 13, thyroid rece|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 31-148 of TRIP13 produced in E.coli|
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