Alfa Aesar™ Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water

Manufacturer: Alfa Aesar™ H51864AE

Quantity 100mL

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Catalog No. AAH51864AE

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    Chemical Identifiers

    CAS 51805-45-9
    Molecular Formula C9H15O6P·HCl
    Linear Formula (HO2CCH2CH2)3P·HCl
    Formula Weight 286.65g/mol
    MDL Number MFCD00145469
    UN Number UN3265
    Synonym TCEP HCl
    Chemical Name or Material Tris(2-carboxyethyl)phosphine hydrochloride

    Specifications

    Quantity 100mL,100mL
    Concentration 0.5M soln. in water
    CAS 51805-45-9
    Molecular Formula C9H15O6P·HCl
    Linear Formula (HO2CCH2CH2)3P·HCl
    Formula Weight 286.65g/mol
    MDL Number MFCD00145469
    UN Number UN3265
    Synonym TCEP HCl
    Health Hazard 1 Danger
    Health Hazard 2 GHS H Statement
    H314
    Causes severe skin burns and eye damage.
    Health Hazard 3 GHS P Statement
    P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
    Do not breathe dust/fume/gas/mist/vapors/spray.
    IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
    IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.
    DOT Information Transport Hazard Class: 8; Packing Group: III; Proper Shipping Name: CORROSIVE LIQUID, ACIDIC, ORGANIC, N.O.S.
    Chemical Name or Material Tris(2-carboxyethyl)phosphine hydrochloride
    Assay 95%

    Description

    Applications
    Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.

    Solubility
    Miscible with water and methanol.

    Notes
    Air sensitive. Store in cool place. Incompatible with strong oxidizing agents

    GHS H Statement
    H314
    Causes severe skin burns and eye damage.

    GHS P Statement
    P260-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
    Do not breathe dust/fume/gas/mist/vapors/spray.
    IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
    IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
    IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
    Store locked up.
    Dispose of contents/container in accordance with local/regional/national/international regulations.

    Danger

    SDS & Safety Documents

  • Description & Specifications
  • Safety and Handling

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