Tris(2-carboxyethyl)phosphine hydrochloride, 98%, Thermo Scientific Chemicals

Description

Reducing agent, specific for disulfides

Reducing agent, specific for disulfidesTris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides, and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Specifications

• Melting Point: 177°C to 178°C
• Color: White
• Linear Formula: (HO₂CCH₂CH₂)₃P·HCl
• Quantity: 0.5 g
• UN Number: UN3261
• Sensitivity: Moisture sensitive
• Merck Index: 14,9085
• Solubility Information: Soluble in water and methanol.
• IUPAC Name: 3-[bis(2-carboxylatoethyl)phosphanyl]propanoate
• Formula Weight: 286.65
• Percent Purity: 98%
• Physical Form: Crystalline Powder
• Chemical Name or Material: Tris(2-carboxyethyl)phosphine hydrochloride

Safety and Handling

Hazard Category	H314-H335
Hazard Statement	GHS H Statement H314-H318 Causes severe skin burns and eye damage. Causes serious eye damage.
Precautionary Statement	P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
DOTInformation	Transport Hazard Class: 8; Packing Group: II; Proper Shipping Name: CORROSIVE SOLID, ACIDIC, ORGANIC, N.O.S.
TSCA	No
Recommended Storage	Ambient temperatures

SDS

RUO – Research Use Only