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TrkA Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA590581

Catalog No. PIPA590581


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Description

Description

Positive Samples: Mouse brain, Rat brain; Cellular Location: Cell membrane, Early endosome membrane, Late endosome membrane, Single-pass type I membrane protein Immunogen sequence: LYRKFTTESD VWSFGVVLWE IFTYGKQPWY QLSNTEAIDC ITQGRELERP RACPPEVYAI MRGCWQREPQ QRHSIKDVHA RLQALAQAPP VYLDVLG

NTRK1 (TRKA) belongs to the neurotrophic factor family of related polypeptides central to the development and maintenance of the mammalian nervous system. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TrkA
Polyclonal
Unconjugated
Ntrk1
C80751, DKFZp781I14186, EC 2.7.10.1, gp140trk, high affinity nerve growth factor receptor, kinase TrkA, MTC, neurotrophic receptor tyrosine kinase 1, Neurotrophic tyrosine kinase receptor type 1, neurotrophic tyrosine kinase, receptor, type 1, Ntrk1, Oncogene TRK, p140-TrkA, Slow nerve growth factor receptor, Tkr, TRK, TRK1, TRK1-transforming tyrosine kinase protein, Trka, Trk-A, TrkA neurotrophin receptor, trkA proto-oncogene receptor, tropomyosin-related kinase A, Tyrosine kinase receptor, Tyrosine kinase receptor A
Rabbit
Affinity Chromatography
RUO
18211, 4914, 59109
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Immunohistochemistry (Paraffin), Western Blot
0.99 mg/mL
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
P04629, P35739, Q3UFB7
Ntrk1
A synthetic peptide corresponding to a sequence within amino acids 700-796 of human TrkA (NP_0025202)
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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