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TrkA Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Thermo Scientific PA598018

Catalog No. PIPA598018


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Description

Description

TrkA (tropomyosin receptor kinase A) encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. TrkA is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of TrkA leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in TrkA have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. Mutations in the TRKA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.
Specifications

Specifications

TrkA
Polyclonal
Unconjugated
NTRK1
Liquid
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
18211, 4914
ELISA, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin)
4.83 mg/mL
PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
P04629, Q3UFB7
Ntrk1
Recombit Human High affinity nerve growth factor receptor protein (33-208AA)
Protein G
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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