TROP-2, Mouse anti-Human, HRP, Clone: TACSTD2/2152, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus Biologicals NBP275746H

Catalog No. NB008805

Description

TROP-2 Monoclonal antibody specifically detects TROP-2 in Human samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin).

Specifications

• Antigen: TROP-2
• Clone: TACSTD2/2152
• Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
• Formulation: PBS with No Preservative
• Gene Symbols: TACSTD2
• Immunogen: Recombinant fragment of human TROP-2 protein (around aa 31-274) (exact sequence is proprietary)
• Monoclonal or Polyclonal: Monoclonal
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Storage Requirements: Store at 4°C in the dark.
• Test Specificity: TROP-2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.

• Applications: Western Blot,Immunohistochemistry,Immunohistochemistry (Paraffin)
• Conjugate: HRP
• Format: Purified,Conjugated
• Gene Alias: Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, TROP2GA7331, tumor-associated calcium signal transducer 2
• Host Species: Mouse
• Isotype: IgG1 Kappa
• Primary or Secondary: Primary
• Quantity: 0.1 mL
• Research Discipline: Signal Transduction
• Target Species: Human