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TRPC5 Mouse anti-Human, Mouse, Rat, Clone: S67-15, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527657

Catalog No. PIMA527657


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Description

Description

TRPC5 belongs to the transient receptor family. TRPC5 is one of the seven mammalian TRPC (transient receptor potential channel) proteins. The TRPC5 protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC5 is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. TRPC5 also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1). TRPC5 is thought to form a receptor-activated non-selective calcium permeant cation channel. TRPC5 is probably operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, or G-protein coupled receptors. TRPC5 has also been shown to be calcium-selective, and may also be activated by intracellular calcium store depletion. Diseases associated with TRPC5 include Hypertrophic Pyloric Stenosis and Pyloric Stenosis.
Specifications

Specifications

TRPC5
Monoclonal
1 mg/ml
PBS with 50% glycerol and 0.09% sodium azide; pH 7.4
Q9QX29, Q9UL62
Htrp5, Short transient receptor potential channel 5, TRP5
Mouse
IgG2b
100 μg
-20°C
Primary
140933, 22067, 7224
Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot
S67-15
Unconjugated
TRPC5
Liquid
Trpc5
Synthetic peptide amino acids 827-845 of human TrpC5 (also known as short transient receptor potential channel 5, and Htrp5)
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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