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Tocris Bioscience™ TRPC6-PAM-C20

Selective TRPC6 positive allosteric modulator

$188.00 - $793.00

Specifications

CAS 667427-75-0
Chemical Name or Material 3-(3-,4-Dihydro-6,7-dimethoxy-3,3-dimethyl-1-isoquinolinyl)-2H-1-benzopyran-2-one
Molecular Formula C22H21NO4
Purity 98%
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
68-751-0
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Tocris Bioscience™
6875/10
10 mg
Each for $188.00
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68-755-0
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Tocris Bioscience™
6875/50
50 mg
Each for $793.00
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Description

Description

  • Selective TRPC6 positive allosteric modulator.
  • Selectively activates TRPC6 over other TRP channels.
  • Also activates TRPA1.
  • Induces transient increase in intracellular Ca2+ in HEK cells expressing TRPC6 (EC50 = 2.37 μM).
  • Potentiates OAG (1-oleoyl-1-acetyl-sn-glycerol)-induced Ca2+ influx in human platelets, and enhances OAG-induced platelet aggregation.
Specifications

Specifications

667427-75-0
3-(3-,4-Dihydro-6,7-dimethoxy-3,3-dimethyl-1-isoquinolinyl)-2H-1-benzopyran-2-one
C22H21NO4
98%
SDS
Product Certifications
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