TSC22D1 Mouse anti-Human, Clone: OTI1A5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526037
DescriptionTSC22 domain family protein, or TSC22, is a transcription factor that belongs to the large family of early response genes. This transcriptional repressor is known to act on the C-type natriuretic peptide (CNP) promoter. TSC22 belongs to the TSC-22/Dip/Bun family and is an intracellular protein that may be found in the cytoplasm or nucleus. This transcription factor is known to regulate cell growth, differentiation and cell death and is involved in modulating the transcriptional activity of Smad3 and Smad4. This protein is ubiquitously expressed in most tissues and widely in both fetal and adult tissues. It is generally expressed in aortic endothelial cells, and induced by cytokines, including TGFB. These proteins may be possible therapeutic targets of leukemia and prostate cancer.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|RP11-269C23.2, Ptg-2, TGFB1I4, TSC22, TGFB-stimulated clone 22 homolog, TGFbeta-stimulated clone 22, TSC22 domain family protein 1, cerebral protein 2, regulatory protein TSC-22, transcriptional regulator TSC-22, transforming growth factor beta-1-induced transcript 4 protein, transforming growth factor beta-stimulated protein TSC-22|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of TSC22D1 produced in HEK293T cell|
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