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TSN Mouse anti-Human, Clone: OTI4C6, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527107

Catalog No. PIMA527107


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Description

Description

Translin is a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. Recent evidence suggests that in combination with a binding partner Trax, Translin binds RNA and mediates trafficking in neurons.
Specifications

Specifications

TSN
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q15631
BCLF-1, RCHF1, REHF-1, TBRBP, TRSLN; recombination hotspot associated factor; recombination hotspot-binding protein
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
7247
Western Blot
OTI4C6
Unconjugated
TSN
Liquid
TSN
Human recombit protein fragment corresponding to amino acids 1-51 of TSN produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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