TSPAN7/TM4SF2 Mouse anti-Human, Alexa Fluor 647, Clone: 482618, R&D Systems™
Mouse Monoclonal Antibody
Manufacturer: R&D Systems FAB9179R025
DescriptionTetraspanin-7 (aka TSPAN7, TALLA-1, TM4SF2 and CD231) is a 249 aminoacids (aa) multi-pass membrane protein. Tetraspanin proteins regulate morphology, signaling and trafficking processes by interaction and association with proteins in tetraspanin enriched microdomains (TEMs). It has been proposed that tetraspanins interact with integrins to affect cell migration, probably by modulation or compartmentalization of integrin signaling. TSPAN7 has been found to be upregulated in myeloma development and described as a prognostic marker of renal cell carcinoma. Mutations in TSPAN7 are also implicated in some forms of X-linked intellectual disability.
|Flow Cytometry 5 uL/10^6 cells|
|A15, A15CCG-B7, CCG-B7, CD231, CD231 antigen, Cell surface glycoprotein A15, DXS1692E, Membrane component chromosome X surface marker 1, mental retardation, X-linked 58, MRX58, MXS1, MXS1T-cell acute lymphoblastic leukemia associated antigen 1, TALLA-1, T-cell acute lymphoblastic leukemia-associated antigen 1, tetraspanin 7, tetraspanin-7, TM4SF2, TM4SF2b, TM4SF2tetraspanin protein, transmembrane 4 superfamily 2b, Transmembrane 4 superfamily member 2X chromosome, surface marker 1, transmembrane protein A15, Tspan-7|
|HEK293 human embryonic kidney cell line transfected with human TSPAN7 Accession # P41732|
|Protein A or G purified from hybridoma culture supernatant|
|Alexa Fluor 647|
|Supplied in a saline solution containing BSA and Sodium Azide. with Sodium Azide|
|Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.|
|Stains human TSPAN7 transfectants but not irrelevant transfectants in flow cytometry.|
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