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TSPAN7/TM4SF2 Mouse anti-Human, Alexa Fluor 647, Clone: 482618, R&D Systems™

Mouse Monoclonal Antibody

Manufacturer:  R&D Systems FAB9179R025

Catalog No. FAB9179R025


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Description

Description

Tetraspanin-7 (aka TSPAN7, TALLA-1, TM4SF2 and CD231) is a 249 aminoacids (aa) multi-pass membrane protein. Tetraspanin proteins regulate morphology, signaling and trafficking processes by interaction and association with proteins in tetraspanin enriched microdomains (TEMs). It has been proposed that tetraspanins interact with integrins to affect cell migration, probably by modulation or compartmentalization of integrin signaling. TSPAN7 has been found to be upregulated in myeloma development and described as a prognostic marker of renal cell carcinoma. Mutations in TSPAN7 are also implicated in some forms of X-linked intellectual disability.
Specifications

Specifications

TSPAN7/TM4SF2
482618
Flow Cytometry 5 uL/10^6 cells
P41732
A15, A15CCG-B7, CCG-B7, CD231, CD231 antigen, Cell surface glycoprotein A15, DXS1692E, Membrane component chromosome X surface marker 1, mental retardation, X-linked 58, MRX58, MXS1, MXS1T-cell acute lymphoblastic leukemia associated antigen 1, TALLA-1, T-cell acute lymphoblastic leukemia-associated antigen 1, tetraspanin 7, tetraspanin-7, TM4SF2, TM4SF2b, TM4SF2tetraspanin protein, transmembrane 4 superfamily 2b, Transmembrane 4 superfamily member 2X chromosome, surface marker 1, transmembrane protein A15, Tspan-7
HEK293 human embryonic kidney cell line transfected with human TSPAN7 Accession # P41732
Protein A or G purified from hybridoma culture supernatant
RUO
Primary
7102
Human
Flow Cytometry
Alexa Fluor 647
Supplied in a saline solution containing BSA and Sodium Azide. with Sodium Azide
Purified
Mouse
IgG2a
25 Tests
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.
Monoclonal
Stains human TSPAN7 transfectants but not irrelevant transfectants in flow cytometry.
SDS
Documents
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