Invitrogen™ TSSK6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567708

Catalog No. PIPA567708

Description

Predicted to react with Mouse and Rat samples.

The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine (Ser/Thr) protein kinases. TSSK 6 (testis-specific serine kinase 6), also known as SSTK, TSSK4, FKSG82 or CT72, is a 273 amino acid protein that contains one protein kinase domain and belongs to the Ser/Thr protein kinase family. Highly expressed in testis with lower expression in ovary, colon, thymus, small intestine and spleen, TSSK 6 catalyzes the ATP-dependent phosphorylation of proteins involved in sperm production and chromatin remodeling. TSSK 6 uses magnesium as a cofactor and is thought to be required for proper sperm development and function, as well as DNA condensation events. Defects in the gene encoding TSSK 6 are associated with male infertility characterized by low sperm count and decreased sperm motility.

Specifications

• Antigen: TSSK6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TSSK6
• Gene Alias: Cancer/testis antigen 72; CT72; FKSG82; RGD1559764; serine/threonine protein kinase SSTK; serine/threonine-protein kinase SSTK; Small serine/threonine kinase; SSTK; testis secretory sperm-binding protein Li 205a; testis specific serine kinase 6; testis-specific kinase 6; testis-specific serine kinase 6; testis-specific serine/threonine-protein kinase 6; TSK-6; TSSK4; TSSK6; TSSK-6
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 290670, 83983, 83984
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q925K9, Q9BXA6
• Gene Symbols: TSSK6
• Immunogen: Synthesized peptide derived from human TSSK6.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG