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TTI1 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 223811AP

Catalog No. 50-173-3853


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Description

Description

Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
Specifications

Specifications

TTI1
0.24 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O43156
KIAA0406, TTI1
Rabbit
IgG
150 μL
-20°C
Primary
9675
Immunoprecipitation, Western Blot
Unconjugated
TTI1
Liquid
TTI1
TTI1 Fusion Protein Ag17697
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
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