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TUBA3E Monoclonal Antibody (OTI2A8), TrueMAB™, OriGene
Mouse Monoclonal Antibody
Supplier: OriGene TA501545
Description
The microtubules are intracellular dynamic polymers made up of evolutionarily conserved polymorphic alpha/beta-tubulin heterodimers and a large number of microtubule-associated proteins (MAPs). Microtubules have their intrinsic polarity; highly dynamic plus ends and less dynamic minus ends. Microtubules are required for vital processes in eukaryotic cells including mitosis, meiosis, maintece of cell shape and intracellular transport. Microtubules are also necessary for movement of cells by means of flagella and cilia. In mammalian tissue culture cells microtubules have their minus ends anchored in microtubule organizing centers (MTOCs).The GTP (guanosintriphosphate) molecule is an essential for tubulin heterodimer to associate with other heterodimers to form microtubule. In vivo, microtubule dynamics vary considerably. Microtubule polymerization is reversible and a populations of microtubules in cells are on their minus ends either growing or shortening - this phenomenon is called dynamic instability of microtubules. The alpha-tubulin (relative molecular weight around 50 kDa) is globular protein that exists in cells as part of soluble alpha/beta-tubulin dimer or it is polymerized into microtubules. In different species it is coded by multiple tubulin genes that form tubulin classes (in human 6 genes).Specifications
TUBA3E | |
Monoclonal | |
1 mg/mL | |
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide | |
Q6PEY2 | |
TUBA3E | |
Full length human recombit protein of human TUBA3E produced in HEK293T cell. | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG2a |
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Western Blot | |
OTI2A8 | |
Unconjugated | |
TUBA3E | |
tubulin alpha 3e | |
Mouse | |
Affinity Chromatography | |
RUO | |
112714 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Liquid |
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