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Thermo Scientific™ Lab Vision™ Tubulin-α Ab-2, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Tubulin-α Ab-2, Mouse Monoclonal Antibody. 

$220.00 - $893.00

Specifications

Antigen Tubulin, alpha Ab-2
Clone DM1A
Applications Immunoassay, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Classification Monoclonal
Conjugate Unconjugated
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Products 7
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Formulation Quantity Price Quantity & Availability  
MS581P
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Thermo Scientific™
MS581P
Purified Ab with BSA and Azide 1mL Each for $893.00
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MS581P0
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Thermo Scientific™
MS581P0
Purified Ab with BSA and Azide 100μL Each for $220.00
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MS581P1
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Thermo Scientific™
MS581P1
Purified Ab with BSA and Azide 500μL Each for $559.50
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MS581P1ABX
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Thermo Scientific™
MS581P1ABX
Purified Ab without BSA and Azide 100μL Each for $619.00
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MS581PABX
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Thermo Scientific™
MS581PABX
Purified Ab without BSA and Azide 200μL Each for $869.00
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MS581R7
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Thermo Scientific™
MS581R7
Ready-to-use for IHC 7mL Each for $287.00
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MS581R1
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Thermo Scientific™
MS581R1
Ready-to-use for IHC 1mL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
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Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ Tubulin-α Ab-2, Mouse Monoclonal Antibody.

Microtubules, the major cytoskeletal elements found in all eukaryotic cells, consist of Tubulin, which is a dimer of two 55kDa subunits: α and Β. Microtubules play key roles in chromosome segregation in mitosis, intracellular transport, ciliary and flagellar bending, and structural support of the cytoskeleton.

Host Species: Mouse

Clone: DM1A

Isotype: IgG1/κ

Species Reactivity: Human, Cow, Pig, Rat, Mouse, Guinea Pig, Gerbil, Frog and Chicken. Others not known.

Epitope: aa 426-450

Immunogen: Native chick brain microtubules

Molecular Weight: 57kDa

Positive Control: Ls174T, MAD109 cells; skin or lung

Cellular Localization: Cytoplasmic Ab-2 causes the 10nm filaments to collapse into large lateral aggregates collecting in the cell periphery or tight juxtanuclear caps. It does not block microtubule assembly. It does not inhibit polymerization or depolymerization of platelet tubulin in vitro. It blocks (by 70-80%) the ability of tubulin dimers (with GppNHp bound) to promote a stable inhibition of adenylyl cyclase.

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Western Blotting
  • Immunofluorescence
  • Immunoprecipitation (Native and denatured)
  • Electron Microscopy

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Tubulin, alpha Ab-2
Immunoassay, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
RUO
Primary
IgG2a kappa
DM1A
Monoclonal
Murine
Cytoskeletal Protein
Native chick brain microtubules
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