Invitrogen™ TUSC3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104363

Catalog No. PIPA5104363

Description

Antibody detects endogenous levels of total TUSC3.

Made up of nearly 146 million bases, chromosome 8 encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Trisomy 8, also known as Warkany syndrome 2, most often results in early miscarriage but is occasionally seen in a mosaic form in surviving patients who suffer to a varying degree from a number of symptoms including retarded mental and motor development, and certain facial and developmental defects. WRN is a DNA helicase encoded by chromosome 8 and shown defective in those with the early aging disorder Werner syndrome. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome.

Specifications

• Antigen: TUSC3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TUSC3
• Gene Alias: AU022242; BC003311; D8S1992; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit TUSC3; M33; Magnesium uptake/transporter TUSC3; MGC13453; MRT22; MRT7; N33; Oligosaccharyl transferase subunit TUSC3; oligosaccharyltransferase 3 homolog A; OST3A; Protein N33; Putative prostate cancer tumor suppressor; tumor suppressor candidate 3; Tusc3
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 290783, 7991, 80286
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q13454, Q8BTV1
• Gene Symbols: TUSC3
• Immunogen: A synthesized peptide derived from human TUSC3(Accession Q13454), corresponding to amino acid residues Y133-A183.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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