Tocris™ TY 52156

S1P3 receptor antagonist

Manufacturer: Tocris™ 5328/50

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Catalog No. 53-285-0

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For Research Use Only


    Description TY 52156
    Quantity 50mg
    Product Type TY 52156
    Molecular Weight 364.27
    Purity >98

    S1P3 receptor antagonist (Ki = 110nM); inhibits S1P-induced Ca2+ release in HUVEC cells. Suppresses FTY-720-induced S1P3 receptor-mediated bradycardia in vivo. Also inhibits S1P-induced breast cancer stem cell expansion in vitro. Orally bioavailable.

    • Chemical Name: N-(4-Chlorophenyl)-3,3-dimethyl-2-oxobutanimidic 2-(4-chlorophenyl) hydrazide
    • Formula: C18H19Cl2N3O
    • CAS Number: 934369-14-9
    • Solubility: Soluble to 100mM in DMSO and to 100mM in ethanol
    • Purity: >98

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