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Invitrogen™ Tyrosine Hydroxylase Polyclonal Antibody
Rabbit Polyclonal Antibody
$514.50 - $1763.00
Specifications
| Antigen | Tyrosine Hydroxylase |
|---|---|
| Concentration | 1 mg/mL |
| Content And Storage | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Applications | Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
PIPA5143524
|
Invitrogen™
PA5143524 |
500 μL |
Each for $1,763.00
|
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PIPA5143622
|
Invitrogen™
PA5143622 |
100 μL |
Each for $514.50
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Description
Tyrosine Hydroxylase Polyclonal Antibody for Western Blot, ICC/IF, IHC (PFA)
Tyrosine hydroxylase (TH) is an enzyme involved in the synthesis of catecholamine neurotransmitters dopamine, epinephrine, and norepinephrine. In all species, catecholamine synthesis is regulated by the interaction of TH with a cofactor, tetrahydrobiopterin (BH4). BH4 binds to the TH catalytic domain, resulting in enzymatic activity. Unlike TH in non-primate species, four human TH mRNA splice variants (hTH1-hTH4) have been isolated. These variants are identical in their catalytic domain, but differ in their N-terminal, regulatory domains. TH is also responsible for the conversion of L-tyrosine to L-dopa. TH plays a key role in the physiology of adrenergic neurons. The role of TH in the synthesis of catecholamine neurotransmitters suggests a correlation between the enzyme and a number of neuropathogenic diseases including: Parkinson's disease, schizophrenia, Segawa syndrome, and dystonia, as well as a variety of cardiovascular diseases.Specifications
| Tyrosine Hydroxylase | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Polyclonal | |
| Liquid | |
| IgG | |
| Human, Mouse, Rat | |
| TH | |
| dystonia 14; DYT14; DYT5b; EC 1.14.16.2; HGNC:11782; Th; TH isoform 3; TH isoform a; th1; TH-4; The; TY3H; TYH; TYH antibody; Tyrosine 3-hydroxylase; tyrosine 3-monooxygenase; tyrosine hydroxylase | |
| TH | |
| Primary | |
| Affinity chromatography |
| 1 mg/mL | |
| Immunohistochemistry (PFA fixed), Western Blot, Immunocytochemistry | |
| Unconjugated | |
| Rabbit | |
| RUO | |
| PBS with 50% glycerol and 5mM sodium azide | |
| P04177, P07101, P24529 | |
| 21823, 25085, 7054 | |
| Full length human TH expressed in and purified from E. coli. | |
| Antibody |
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