TYRP1 Mouse, Clone: SPM456, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP2329070.02MG

Catalog No. NBP232907F

Description

TYRP1 Monoclonal specifically detects TYRP1 in Human, Mouse samples. It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.

Specifications

• Antigen: TYRP1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Formulation: PBS with 0.05% BSA. with 0.05% Sodium Azide
• Gene Alias: b-PROTEIN, CAS25,6-dihydroxyindole-2-carboxylic acid oxidase, Catalase B, CATB, EC 1.14.18, EC 1.14.18.-, EC 1.14.18.1, Glycoprotein 75, GP75DHICA oxidase, Melanoma antigen gp75, TRP-1, TRPTYRP, tyrosinase-related protein 1TRP1, TYRRP
• Host Species: Mouse
• Molecular Weight of Antigen: 75 kDa
• Quantity: 0.02 mg
• Primary or Secondary: Primary
• Test Specificity: It reacts with a 75kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1). It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death.
• Content And Storage: Store at 4C.
• Isotype: IgG2a κ

• Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
• Clone: SPM456
• Dilution: Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
• Gene Accession No.: P17643
• Gene Symbols: TYRP1
• Immunogen: SK-MEL-23 cells
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Gene ID (Entrez): 7306
• Target Species: Human, Mouse
• Form: Purified