U2AF1L4 Mouse anti-Human, Clone: OTI7B12, lyophilized, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene CF810433
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCORNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3 ft.-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3 ft.-splice site.
|Full length human recombit protein of human U2AF1L4 produced in E.coli.|
|PBS with 8% trehalose and no preservative; pH 7.3|
|U2AF1-RS3, U2AF1L3, U2AF1L3V1, U2AF1RS3, U2af26|
|-20° C, Avoid Freeze/Thaw Cycles|
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