Potent inhibitor of dipeptidyl peptidase II (DPP-II) (IC50 = 0.48nM). Exhibits selectivity for DPP-II against DPP-9, DPP-8 and DPP-IV (IC50 values are 78.6, 142 and 165µM, respectively). Orally available.
Chemical Name: (2S)-2-Amino-4-[[(4-chlorophenyl)methyl]amino]-1-(1-piperidinyl)-1-butanone dihydrochloride
CAS Number: 697797-51-6
Solubility: Soluble to 100mM in water and to 100mM in DMSO
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