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UAP1L1 Rabbit anti-Human, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 252621AP

Catalog No. 50-173-4821


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Description

Description

UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a alpha/beta structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males.
Specifications

Specifications

UAP1L1
0.43 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q3KQV9
UAP1L1
Rabbit
IgG
150 μL
-20°C
Primary
91373
Immunocytochemistry, Immunofluorescence, Western Blot
Unconjugated
UAP1L1
Liquid
UAP1L1
Peptide
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human
Documents
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