UBA3 Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI1B9, liquid, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene TA811881

Catalog No. 50-168-4313

Description

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Specifications

• Antigen: UBA3
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q8C878, Q8TBC4, Q99MI7
• Gene Symbols: UBA3
• Immunogen: Human recombit protein fragment corresponding to amino acids 1-463 of human UBA3 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Canine, Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1B9
• Conjugate: Unconjugated
• Gene: UBA3
• Gene Alias: NAE2, UBE1C, hUBA3
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 117553, 22200, 476560, 9039
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid