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UBA3 Mouse anti-Canine, Human, Mouse, Rat, Clone: OTI1B9, liquid, TrueMAB™
Mouse Monoclonal Antibody
Supplier: OriGene TA811881
SDSDocumentsProduct Certifications Promotions
DescriptionThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|Q8C878, Q8TBC4, Q99MI7|
|Human recombit protein fragment corresponding to amino acids 1-463 of human UBA3 produced in E.coli.|
|Canine, Human, Mouse, Rat|
|NAE2, UBE1C, hUBA3|
|117553, 22200, 476560, 9039|
|-20° C, Avoid Freeze/Thaw Cycles|
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