UBE2T Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA550159
The antibody detects endogenous levels of total UBE2T protein.UBE2T is involved in the covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3). UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates. Functionally, UBE2T accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, catalyzes monoubiquitination, is involved in mitomycin-C (MMC)-induced DNA repair, and catalyzES monoubiquitination of FANCD2, a key step in the DNA damage pathway. Defects in the UBE2T gene have been associated with Fanconi anemia of complementation group T.
|Synthesized peptide derived from internal of human UBE2T.|
|Antigen affinity chromatography|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.4|
|Ubiquitin-conjugating enzyme E2 T, Ubiquitin-protein ligase T, Ubiquitin carrier protein T, UBE2T,|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok