UBE2T Mouse anti-Human, Clone: OTI2F5, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525226
DescriptionUBE2T is involved in the covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3). UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates. Functionally, UBE2T accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, catalyzes monoubiquitination, is involved in mitomycin-C (MMC)-induced DNA repair, and catalyzES monoubiquitination of FANCD2, a key step in the DNA damage pathway. Defects in the UBE2T gene have been associated with Fanconi anemia of complementation group T.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|PIG50, HSPC150 protein similar to ubiquitin-conjugating enzyme, cell proliferation-inducing gene 50 protein, ubiquitin carrier protein T, ubiquitin conjugating enzyme, ubiquitin-conjugating enzyme E2 T, ubiquitin-protein ligase T|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|Full length human recombit protein of UBE2T produced in HEK293T cell|
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