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UBE2T Mouse anti-Human, Clone: OTI2F5, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA525226

Catalog No. PIMA525226


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Description

Description

UBE2T is involved in the covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3). UBE2T catalyzes the covalent attachment of ubiquitin to protein substrates. Functionally, UBE2T accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins, catalyzes monoubiquitination, is involved in mitomycin-C (MMC)-induced DNA repair, and catalyzES monoubiquitination of FANCD2, a key step in the DNA damage pathway. Defects in the UBE2T gene have been associated with Fanconi anemia of complementation group T.
Specifications

Specifications

UBE2T
Monoclonal
0.33 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9NPD8
PIG50, HSPC150 protein similar to ubiquitin-conjugating enzyme, cell proliferation-inducing gene 50 protein, ubiquitin carrier protein T, ubiquitin conjugating enzyme, ubiquitin-conjugating enzyme E2 T, ubiquitin-protein ligase T
Mouse
IgG2a
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
29089
Immunocytochemistry, Immunofluorescence, Western Blot
OTI2F5
Unconjugated
UBE2T
Liquid
UBE2T
Full length human recombit protein of UBE2T produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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