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UBE2U Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 173231AP

Catalog No. 50-173-1508


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Description

Description

The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires ATP-dependent activation of the Ub C-terminus and assembly of multi-Ub chains by a Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2U (ubiquitin-conjugating enzyme E2U) is a 321 amino acid E2 ubiquitin conjugating enzyme that catalyzes the covalent attachment of ubiquitin to other proteins. Existing as two alternatively spliced isoforms, UBE2U is encoded by a gene located on human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Specifications

Specifications

UBE2U
0.2 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Q5VVX9
RP4 636O23.1, UBE2U, Ubiquitin carrier protein U, Ubiquitin protein ligase U
Rabbit
IgG
150 μL
-20°C
Primary
148581, 381534
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
UBE2U
Liquid
UBE2U
UBE2U Fusion Protein Ag11302
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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