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UBE2V1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Encompass_Preferred

$395.30

Specifications

Antigen UBE2V1
Concentration 0.25 mg/mL
Applications Western Blot
Conjugate Unconjugated
Format Liquid
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-172-6112
Encompass_Preferred
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Proteintech Group IncSupplier Diversity Partner
102072AP150UL
150 μL
Each for $395.30
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Description

Description

Ubiquitin-conjugating enzyme E2 (UEV1) was initially discovered as a protein similar in sequence and structure to the E2 ubiquitin-conjugating enzymes but lacking their enzymatic activity. There are at least two variants and multiple isoforms of UEV1. In particular, UEV1A (Ubiquitin-conjugating enzyme E2 variant 1 isoform A) has recently been shown to be an important component of the Toll-like receptor and IL-1R signaling pathway. Signals from these pathways are relayed by a number of downstream molecules such as MyD88 and tumor necrosis factor receptor associated factor (TRAF6), ultimately activating various kinases and transcription factors. UEV1A is part of a dimeric ubiquitin-conjugating enzyme complex also containing Ubc13 (ubiquitin-conjugating enzyme 13) that together with TRAF6 activates TAK1, a member of the mitogen-activated protein kinase family. The Ubc13-UEV1A complex also mediates the Lys-63 ubiquitination of TRAF-6, and this ubiquitination is essential for TAK1 activation.
Specifications

Specifications

UBE2V1
Western Blot
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Polyclonal
-20°C
0.25 mg/mL
Unconjugated
Rabbit
Human, Mouse, Rat
IgG
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications
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