Ubiquitin Monoclonal Antibody (P4D1), Active Motif™

Mouse Monoclonal Antibody

Supplier:  Active Motif 39741

Catalog No. 50-199-2815

Description

Ubiquitin, a highly conserved protein that has a major role in targeting cellular proteins for degradation by the 26S proteosome, is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin fused to an unrelated protein. This gene encodes a fusion protein consisting of ubiquitin at the N terminus and ribosomal protein S27a at the C terminus. When expressed in yeast, the protein is post-translationally processed, generating free ubiquitin monomer and ribosomal protein S27a. Ribosomal protein S27a is a component of the 40S subunit of the ribosome and belongs to the S27AE family of ribosomal proteins. It contains C4-type zinc finger domains and is located in the cytoplasm. Pseudogenes derived from this gene are present in the genome. As with ribosomal protein S27a, ribosomal protein L40 is also synthesized as a fusion protein with ubiquitin; similarly, ribosomal protein S30 is synthesized as a fusion protein with the ubiquitin-like protein fubi.

Specifications

• Antigen: Ubiquitin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
• Gene Accession No.: P62987
• Gene Symbols: UBA52
• Immunogen: This Ubiquitin antibody was raised against purified bovine ubiquitin.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

• Applications: Dot Blot
• Clone: P4D1
• Conjugate: Unconjugated
• Gene: UBA52
• Gene Alias: 60S ribosomal protein L40; BOS_7110; CEP52; D8Ertd21e; Gm1863; HUB L40; HUBCEP52; L40; Large ribosomal subunit protein eL40; MGC127041; RPL40; RPS27A; UBA52; Ubb; UBC; UBCEP2; Ubiquitin; Ubiquitin A-52 residue ribosomal protein fusion product 1; ubiquitin and ribosomal protein L40; ubiquitin carboxyl extension protein 52; ubiquitin/60S ribosomal fusion protein; ubiquitin-52 amino acid fusion protein; Ubiquitin-60S ribosomal protein L40; ubiquitin-CEP52
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 7311
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid