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Tocris Bioscience™ UBP 310

GluK1-selective kainate antagonist

Supplier:  Tocris Bioscience™ 3621/50

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Catalog No. 36-215-0R


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Description

Description

UBP 310 is a GluK1 (formerly GLUK5) kainate receptor antagonist (IC50 = 130 nM); also blocks recombinant homomeric GluK3 (forrmerly GLUK7) receptors. Displays 12,700-fold selectivity for GluK1 (formerly GLUK5) over GluK2 (formerly GLUK6). Exhibits no activity at mGlu group I or NMDA receptors at concentrations of up to 10 μM. Apparent KD value is 18 ± 4 nM for depression of kainate responses on the dorsal root.

Please refer to IUPHAR Guide to Pharmacology for the most recent naming conventions.

Specifications

Specifications

>98%
UBP 310
UBP 310
50 mg
353.35
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