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UBXN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

$395.30

Specifications

Antigen UBXN1
Concentration 0.31 mg/mL
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-173-0744
SDP
Encompass_Preferred
View Documents
Proteintech Group Inc
161351AP150UL
150 μL
Each of 1 for $395.30
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Description

Description

Covalent attachment of the C-terminus of ubiquitin to cellular proteins plays a role in a variety of cellular processes. Ubiquitin C-terminal hydrolysis is catalyzed by deubiquitinating (DUB) enzymes and is necessary for several functions, including liberation of monomeric ubiquitin from the precursors encoded by ubiquitin genes and recycling of ubiquitin monomers. There are 2 distinct families of DUBs, ubiquitin-specific proteases (UBPs) and ubiquitin C-terminal hydrolases (UCHs). Mayer and Wilkinson (1989) identified 4 distinct UCH activities from bovine thymus. All 4 were thiol proteases and had high-affinity binding sites for ubiquitin. Wilkinson et al. (1989) purified the predomit isozyme, UCHL3, and raised antibodies against it. By screening a human B-cell expression library with the antibodies, the authors isolated cDNAs encoding human UCHL3. Sequence comparisons revealed that the sequence of the predicted 230-amino acid human UCHL3 protein is 54% identical to that of UCHL1.
Specifications

Specifications

UBXN1
Western Blot
Unconjugated
Rabbit
Human, Mouse, Rat
IgG
-20°C
0.31 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications
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