Tocris™ UC 112

IAP and XIAP inhibitor; antitumor

Manufacturer: Tocris™ 5251/10

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Catalog No. 52-511-0

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For Research Use Only


    Inhibitors UC 112
    Purity >98
    Molecular Weight 348.44
    Quantity 10mg
    Product Type UC 112

    IAP inhibitor (IC50 values from 0.7 - 3.4µM); inhibits cell growth in multiple cancer cell lines and in a melanoma xenograft model in vivo. Also suppresses X-linked inhibitor of apoptosis protein (XIAP) and survivin levels. Inhibits the growth of P-glycoproteins and activates caspase-3/7 and caspase-9.

    • Chemical Name: 5-[(Phenylmethoxy)methyl]-7-(1-pyrrolidinylmethyl)-8-quinolinol
    • Formula: C22H24N2O2
    • CAS Number: 383392-66-3
    • Solubility: Soluble to 100mM in DMSO
    • Purity: >98

  • Description & Specifications

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