UCH-L1/PGP9.5 Mouse anti-Human, Mouse, Rat, Porcine, Bovine, Zebrafish, Alexa Fluor 350, Clone: 31A3, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP233130AF350
DescriptionUCH-L1/PGP9.5 Monoclonal antibody specifically detects UCH-L1/PGP9.5 in Human,Mouse,Rat,Porcine,Bovine,Zebrafish samples. It is validated for Western Blot,ELISA.
|Western Blot, ELISA|
|EC 126.96.36.199, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1|
|Store at 4°C in the dark.|
|This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson′s disease.|
|ELISA, Western Blot|
|Alexa Fluor™ 350|
|50 mM sodium borate with 0.05% sodium azide|
|Native UchL1 (PGP9.5) protein from brain was used as immunogen to generate the antibody (Day & Thompson, 1986).|
|Bovine, Human, Mouse, Porcine, Rat, Zebrafish|
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