UCH-L1/PGP9.5, Mouse anti-Human,Rat, HRP, Clone: rUCHL1/775, Novus Biologicals™
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP275775H
DescriptionUCH-L1/PGP9.5 Monoclonal antibody specifically detects UCH-L1/PGP9.5 in Human, Rat samples. It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin).
|Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin|
|PBS with No Preservative|
|Recombinant full-length human UCH-L1 protein|
|Protein A or G purified|
|Store at 4°C in the dark.|
|This MAb reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UCH-L1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.|
|Western Blot,Immunohistochemistry,Immunohistochemistry (Paraffin)|
|EC 220.127.116.11, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1|
|Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission|
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