BioVision Inc UGT Activity Assay / Ligand Screening Kit (Fluorometric): UGT Activity Assay / Ligand Screening Kit (Fluorometric): Fluorometric kit on the market to measure UGT activity. Simple & rapid. Detection limit: less than 0.1 mU. 100 assays.
Manufacturer: BioVision Inc K692100
UGT Activity Assay / Ligand Screening Kit (Fluorometric): Uridine diphospho-glucuronosyltransferases (UGTs, EC 188.8.131.52) are a superfamily of microsomal membrane-bound glycosyltransferase enzymes.BioVision's UGT Activity Assay / Ligand Screening Kit utilizes a highly fluorescent UGT substrate with a large Stokes shift (Ex/Em = 415/502 nm) that allows determination of UGT activity by tracking the drop in fluorescence emission as the substrate is converted into a non-fluorescent glucuronide. The multi-isozyme substrate is glucuronidated by virtually all of the pharmacologically-relevant mammalian UGT1A and UGT2B enzymes. The assay is highly sensitive, simple to perform and high-throughput adaptable. This assay can detect less than 0.1 mU UGT activity in biological samples. The kit contains a complete set of reagents sufficient for performing 100 reactions at a 100 ?l reaction volume BioVision charges an Ice pack and Insulated Container fee of $25.00 for each order.
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