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Tocris Bioscience™ UNC 3230

Potent and selective PIP5K1C inhibitor; antinociceptive

Supplier:  Tocris Bioscience™ 5271/50

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Catalog No. 52-715-0


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Description

Description

UNC 3230 is a potent and selective PIP5K1C inhibitor (IC50 = 41 nM). Exhibits selectivity for PIP5K1C over PIP5K1A, the PI 3-kinase family and a panel of other kinases. Reduces PIP2 levels and LPA-induced calcium signaling in dorsal root ganglia (DRG) neurons in vitro. Reduces nociception in mouse models of chronic pain.
Specifications

Specifications

>99%
UNC 3230
UNC 3230
50 mg
344.43
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