Uroplakin III, Rabbit anti-Human, Alexa Fluor 350, Polyclonal, Novus Biologicals™

Rabbit Polyclonal Antibody

Supplier:  Novus Biologicals NBP233126AF350

Catalog No. NB005670

Description

Uroplakin III Polyclonal specifically detects Uroplakin III in Human samples. It is validated for Western Blot.

Specifications

• Antigen: Uroplakin III
• Classification: Polyclonal
• Dilution: Western Blot, Flow Cytometry, Immunocytochemistry/Immunofluorescence
• Gene Alias: MGC119178, UP3a, UPIII, UPIIIA, UPK3, UPK3A, uroplakin 3, uroplakin 3A, Uroplakin III, uroplakin3a, uroplakin-3a
• Host Species: Rabbit
• Purification Method: Protein A purified
• Regulatory Status: RUO
• Test Specificity: Uroplakin-3A (UPK3A) is a component of the asymmetric unit membrane (AUM). It is a highly specialized bio-membrane made by terminally differentiated urothelial cells. The protein may play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. UPK3A also contributes to the formation of urothelial glycocalyx, which may play an important role in preventing bacterial adherence through FimH bacterial protein binding leading to bladder infection. UPK3A has been shown as a helpful marker for the detection of bladder cancer.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
• Conjugate: Alexa Fluor 350
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: UPK3A
• Immunogen: A synthetic peptide, aa260-279 (GASESSYTSVNRGPPLDRAE) of human UPK3A
• Quantity: 0.1 mL
• Primary or Secondary: Primary
• Target Species: Human
• Isotype: IgG