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USP34 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 188271AP150UL
Description
The antibody recognize all 3 isoforms of USP34.
Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.Specifications
USP34 | |
Polyclonal | |
Unconjugated | |
USP34 | |
Deubiquitinating enzyme 34, KIAA0570, KIAA0729, Ubiquitin thiolesterase 34, USP34 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
17847, 9736 | |
-20°C | |
Liquid |
Immunohistochemistry (Paraffin), Western Blot | |
0.13 mg/mL | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Q6ZQ93, Q70CQ2 | |
Usp34 | |
Peptide | |
150 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
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