Invitrogen™ USP49 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA556417

Catalog No. PIPA556417

Description

Immunogen sequence: ECFLNLDPSK TEHLFPKATN GKTQLSGKPT NSSATELSLR NDRAEACERE GFCWNGRASI SRSLELIQNK EPSSK Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 68%.

Specifically deubiquitinates histone H2B at 'Lys-120' (H2BK120Ub). H2BK120Ub is a specific tag for epigenetic transcriptional activation and acts as a regulator of mRNA splicing. Deubiquitination is required for efficient cotranscriptional splicing of a large set of exons.

Specifications

• Antigen: USP49
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: USP49
• Gene Alias: C330046L10Rik; deubiquitinating enzyme 49; Gm545; RGD1310513; ubiquitin carboxyl-terminal hydrolase 49; ubiquitin specific peptidase 49; ubiquitin specific protease 49; ubiquitin thioesterase 49; ubiquitin thiolesterase 49; ubiquitin-specific-processing protease 49; Usp49
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 25862
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q70CQ1
• Gene Symbols: USP49
• Immunogen: Recombinant protein corresponding to Human USP49. Recombinant protein control fragment (Product #RP-94934).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG