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USP6 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549448

Catalog No. PA549448

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

USP6 is a deubiquitinase with an ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety. It catalyzes its own deubiquitination. In vitro, isoform2, but not isoform3, shows deubiquitinating activity. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It is able to initiate tumorigenesis by inducing the production of matrix metalloproteinases following NF-kappa-B activation.
Specifications

Specifications

USP6
Polyclonal
PBS with 0.09% sodium azide
P35125
Ubiquitin carboxyl-terminal hydrolase 6, Deubiquitinating enzyme 6, Proto-oncogene TRE-2, Ubiquitin thioesterase 6, Ubiquitin-specific-processing protease 6, USP6, HRP1, TRE2
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
9098
Flow Cytometry, Western Blot
Unconjugated
USP6
Liquid
USP6
KLH conjugated synthetic peptide between 1280-1310 amino acids from the C-terminal region of human USP6.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Documents
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