Vγ 2 T-Cell Receptor Hamster anti-Mouse, Brilliant Violet 510, Clone: UC3-10A6, BD Optibuild™
Armenian Hamster Monoclonal Antibody
Manufacturer: BD Biosciences 742309
The UC3-10A6 monoclonal antibody specifically recognizes T-cell Receptor (TCR) V gamma 2 (Vγ2).Vγ2+ TCRγδcells make up significant proportions of TCRγδcells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung. The frequency of splenicVγ2+ TCRγδcells differs among inbred mouse strains; in C57BL/6 mice, the frequency increases dramatically during the four weeks after birth. Immobilized UC3-10A6 antibody can activateVγ2+TCRγδ cells. Please note that the Vγ2 designation correlates with the nomenclature of Garman, Doherty, and Raulet; the Vγ4 designation of Heiligand Tonegawa is equilvalent.The antibody was conjugated to BD Horizon™ BV510 which is part of the BD Horizon Brilliant™ Violet family of dyes. With an Ex Max of 405nm and Em Max at 510nm, BD Horizon BV510 can be excited by the violet laser and detected in the BD Horizon V500 (525/50nm) filter set. BD Horizon BV510 conjugates are useful for the detection of dim markers off the violet laser. BV510 is a polymer-based dye that is brighter than BD Horizon V500. Due to similar excitation and emission properties, BD Horizon BV510 and BD Horizon V500 cannot be used simultaneously.
|Vγ 2 T-Cell Receptor|
|Aqueous buffered solution containing ≤0.09% sodium azide.|
|V gamma 2 TCR, Vγ2 TCR, Trgv2|
|The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography. The antibody was conjugated with BD Horizon BV510 under optimal conditions that minimize unconjugated dye and antibody.|
|Brilliant Violet 510|
|Armenian Hamster IgG1, κ|
|Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.|
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