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VAMP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Encompass_Preferred

Specifications

Antigen VAMP2
Concentration 0.29 mg/mL
Applications Immunohistochemistry (Paraffin), Western Blot
Conjugate Unconjugated
Format Liquid
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Products 1
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-172-6050
Encompass_Preferred
View Documents Promotion Details
Proteintech Group IncSupplier Diversity Partner
101351AP150UL
150 μL
Each for $395.30
N/A
Description

Description

The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP-25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer′s disease, VAMP levels of all isoforms appear to be significantly lowered. It is suggested that VAMP-2 is a resident protein of the insulin-sensitive glucose transporter type 4 (GLUT4) compartment and that it is required for GLUT4 vesicle incorporation into the cell surface in response to insulin.
Specifications

Specifications

VAMP2
Immunohistochemistry (Paraffin), Western Blot
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Polyclonal
-20°C
0.29 mg/mL
Unconjugated
Rabbit
Human, Mouse, Rat
IgG
Antigen Affinity Chromatography
Antibody
SDS
Product Certifications
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