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VANGL2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 214921AP

Catalog No. 50-173-3447


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Description

Description

Van Gogh is an alternate name for the Drosophila strabismus protein. Van Gogh like-2 (VANGL2) is a 521 amino acidprotein in vertebrates similar to strabismus 1 of Drosophila and a component of the frizzled-disheveled tissue polarity pathway. It interacts through it ft.s C-terminal region with the N-terminal half of DVL1, DVL2 and DVL3 and is a potent tumor suppressor. It ispredomitly involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a crucial role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. VANGL2 is required for polarization and movement of myocardializing cells and seems to act via RHOA signaling to regulate this process. It is expressed in a wide range of tissues.
Specifications

Specifications

VANGL2
0.23 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P84889, Q91ZD4, Q9ULK5
KIAA1215, Loop tail protein 1 homolog, LPP1, LTAP, STB1, STBM, STBM1, Strabismus 1, Van Gogh like protein 2, Vang like protein 2, VANGL2
Rabbit
IgG
150 μL
-20°C
Primary
289229, 57216, 93840
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
VANGL2
Liquid
Vangl2
VANGL2 Fusion Protein Ag15833
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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