VDAC Recombinant Rabbit Monoclonal Antibody, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Supplier:  Thermo Scientific MA533205

Catalog No. PIMA533205

Description

Voltage-dependent anion channel (VDAC) proteins are abundant, pore-forming proteins belonging to the eukaryotic mitochondrial porins. It was discovered in the mitochondrial outer membrane. It also is expressed in the plasma membrane. At least three different VDAC genes have been identified in vertebrates. VDAC proteins are known to play an essential role in cellular metabolism and in the early stages of apoptosis. For example, VDAC contitutes a major pathway by which metabolites such as ADP/ATP, succinate and citrate are exchanged between the cytosol and mitochondria. And VDAC1 in the plasma membrane establishes a novel level of apoptosis regulation putatively via its redox activity.

Specifications

• Antigen: VDAC
• Classification: Recombinant Monoclonal
• Conjugate: Unconjugated
• Gene: VDAC1
• Gene Symbols: Vdac1
• Immunogen: A synthesized peptide derived from human VDAC1
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.11 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: P21796, Q60932, Q9Z2L0
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 22333, 7416, 83529
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid