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VEGF R2/KDR/Flk-1 Mouse anti-Human, Clone: KDR657, Novus Biologicals™
Mouse Monoclonal Antibody
Supplier: Novus Biologicals NBP2330000.2MG
SDSDocumentsProduct Certifications Promotions
DescriptionVEGF R2/KDR/Flk-1 Monoclonal antibody specifically detects Antigen in Human samples. It is validated for Flow Cytometry, Immunofluorescence.
|PBS with 0.05% BSA. with 0.05% Sodium Azide|
|CD309, CD309 antigen, EC 2.7.10, EC 18.104.22.168, Fetal liver kinase 1, fetal liver kinase-1, FLK-1, FLK1tyrosine kinase growth factor receptor, Kinase insert domain receptor, kinase insert domain receptor (a type III receptor tyrosine kinase), Protein-tyrosine kinase receptor flk-1, soluble VEGFR2, vascular endothelial growth factor receptor 2, VEGFR, VEGFR2, VEGFR-2|
|Protein A purified|
|CD309, also known as VEGF-R2, KDR3, and Flk-1 (mouse), is a type I transmembrane glycoprotein. It is a member of the CSF-1/PDGF receptor family of type III tyrosine kinase receptors. Human VEGF-R2 is mainly expressed by endothelial cells, embryonic tissues, and megakaryocytes. It plays an important role in the regulation of angiogenesis, vasculogenesis, and vascular permeability. The ligands of VEGF-R2 include VEGF-A, VEGF-C, VEGF-D, and VEGF splice isoforms. Ligation of VEGF-R2 with its ligands results in the receptor dimerization and auto-phosphorylation, stimulating endothelial cell proliferation and migration.|
|Store at 4C.|
|Flow Cytometry, Immunofluorescence|
|Flow Cytometry 0.5 - 1ug/million cells in 0.1ml, Immunofluorescence 0.5 - 1ug/ml|
|Recombinant human VEGF-R2 protein|
|Angiogenesis, Cancer, Cellular Markers, Endothelial Cell Markers, Hematopoietic Stem Cell Markers, HIF Target Genes, Hypoxia, Phospho Specific, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases|
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