VEGFR1/Flt-1 Mouse anti-Human, Alexa Fluor 350, Clone: FLT1/658, Novus Biologicals
Mouse Monoclonal Antibody
Manufacturer: Novus Biologicals NBP234618AF350
DescriptionVEGFR1/Flt-1 Monoclonal antibody specifically detects VEGFR1/Flt-1 in Human samples. It is validated for ELISA.
|EC 2.7.10, EC 126.96.36.199, FLT, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGFR1, VEGFR-1|
|Store at 4°C in the dark.|
|Three cell membrane receptor tyrosine kinases, Flt-1 (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt-1 and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.|
|Alexa Fluor™ 350|
|50 mM sodium borate with 0.05% sodium azide|
|Recombinant human VEGF-R1 protein|
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