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VEGFR1/Flt-1 Mouse anti-Human, Alexa Fluor™ 750, Clone: FLT1/659, Novus Biologicals™

Mouse Monoclonal Antibody

Manufacturer:  Novus BiologicalsSupplier Diversity Partner NBP234619AF750

Catalog No. NP234619A70


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Description

Description

VEGFR1/Flt-1 Monoclonal antibody specifically detects VEGFR1/Flt-1 in Human samples. It is validated for ELISA.
Specifications

Specifications

VEGFR1/Flt-1
FLT1/659
ELISA
Conjugated, Purified
FLT1
Recombinant human VEGF-R1 protein
Protein A purified
Angiogenesis, Cancer, Cellular Markers, Endothelial Cell Markers, HIF Target Genes, Hypoxia, Myeloid derived Suppressor Cell, Phospho Specific, Signal Transduction, Stem Cell Markers, Tumor Suppressors, Tyrosine Kinases
Primary
2321.0
Human
ELISA
Alexa Fluor™ 750
50 mM sodium borate with 0.05% sodium azide
EC 2.7.10, EC 2.7.10.1, FLT, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGFR1, VEGFR-1
Mouse
IgG1 Kappa
0.1 mL
Store at 4°C in the dark.
Monoclonal
Three cell membrane receptor tyrosine kinases, Flt-1 (also designated VEGF-R1), Flk-1 (also designated VEGF-R2) and Flt-4, putatively involved in the growth of endothelial cells, are characterized by the presence of seven immunoglobulin-like sequences in their extracellular domain. These receptors exhibit high degrees of sequence relatedness to each other as well as lesser degrees of relatedness to the class III receptors including CSF-1/Fms, PDGR, SLFR/Kit and Flt-3/Flk-2. Two members of this receptor class, Flt-1 and Flk-1, have been shown to represent high affinity receptors for vascular endothelial growth factors (VEGFs). On the basis of structural similarity to Flt-1 and Flk-1, it has been speculated that Flt-4 might represent a third receptor for either VEGF or a VEGF-related ligand.
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