VIM Mouse anti-Human, Clone: 23H2, Abnova™
Mouse monoclonal antibody raised against human VIM.
Manufacturer: Abnova Corporation MAB12665
This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract
|Mouse monoclonal antibody raised against human VIM.|
|In HEPES, 0.15M NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide).|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:400) Immunoprecipitation Western Blot (1:2000) The optimal working dilution should be determined by the end user.|
|Recombinant protein corresponding to human VIM.|
|Ammonium sulfate precipitation|
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